100 new jobs have been announced for Cork, Dublin and Galway.
The IDA says the roles are being created by five different 'high growth companies from Europe and the US'.
Health technology company, Movano Health is expanding its Cork operations with 20 new jobs, while pharmaceuticals company QbDVision is also bringing 15 new jobs to Cork.
Payments company Total Processing plans to create 25 new jobs, while Alliance Strategies has announced 15 new marketing and finance roles in Galway.
The remaining jobs will be created by software company Xenon arc when it opens a new EMEA customer support and operations office in Dublin.