Gardaí made the seizure at a house in the town last night.
Gardaí from the Drugs Unit in Togher carried out a search warrant at a house in Carrigaline at around 09:30pm.
Around €96,500 worth of suspected cocaine, €5,400 of ketamine, €2,000 worth of MDMA and €1,800 worth of cannabis was found.
A man in his 20s is being detained under drug trafficking legislation, while the drugs seized will be sent for further analysis
Gardaí say the raid is part of an ongoing operation targeting the sale and supply of drugs in Cork.