Dr Ronan Glynn says trust and transparency is the cornerstone of the Department of Health's approach to ensuring people get the injection when they are eligible.
It's been less than 12 months since Covid-19 was reported to the World Health Organisation, and already there are a number of candidate vaccines - while the Pfizer BioNTech shot is already being administered in parts of the world.
It usually takes up to 10 years for a vaccine to be developed however, Dr Ronan Glynn says the speed shouldn't be cause for alarm.
He says there has been scientific and medical research carried out on a scale which has never been seen before, while the high number of Covid-19 cases means the trials were quickly able to see what was working, and what wasn't.
The Deputy Chief Medical Officer also says the ability of pharmaceutical companies to run different phases in parallel with each other allowed the process to be quicker.
Research from the Department of Health shows 45% of people will definitely take a vaccine when they're eligible, while 28% say they will probably take one.
Dr Ronan Glynn says there will be rumour and misinformation online about a vaccine but says public health officials will have to build confidence and address uncertainties.
