The State's Chief Medical Officer is making the appeal, saying gatherings in homes are taking place "with abandon" across the country.
Residents associations have staged a number of protests in the area around UCC in the past week after students moved back to the area.
Five more people with the virus have died, bringing the death toll to 1,664, while there have been 25,142 confirmed cases since the crisis began here in late February.
CMO Dr. Tony Holohan says house parties shouldn't be happening currently: