686 children aged between 10 and 17 were hospitalised for alcohol or drug-related illnesses last year.
Over twice as many girls as boys needed treatment, in this age-group.
A further 228 children, who were less than nine years old, were hospitalised for these conditions in 2020.
Consultant paediatrician Ciara Martin, from Children's Health Ireland, says some teenagers get very sick from alcohol-poisoning.