Gardaí are seeking the public's assistance in tracing the whereabouts of 2-year-old, Aoife Haynes Murphy.
Aoife was taken from Swinford Health Centre, Co. Mayo at around 10:10am today.
Aoife is understood to be currently travelling with her parents, 33 year old Paul Murphy and 34 year old Kimberley Haynes in a Black Kia Sportage car with registration number KE21ENH.
Gardaí say they have serious concerns that there is an immediate and serious risk to Aoife.
It's believed Aoife and her parents are in Dublin City Centre area at this time.
Aoife has fair coloured hair and at the time she went missing was wearing a pink body suit with a checked dress, cream tights, pink dock martin boots and an animal print jacket with a hood. The jacket is very distinctive as it contains of a number of animal prints including giraffes, zebras, monkeys and elephants.
Paul is described as being 5 foot 6 inches in height with a slight build with shaved hair.
Kimberley is described as being 5 foot 8 in height of slim build with long straight black hair.
Anyone with information is asked to contact Gardaí on 999 or 112.
Please do not approach those involved, instead immediately contact 999 / 112 or your local Garda Station providing as much information as possible.
People are asked not to call the Garda Confidential Line as it is not open on a 24/7 basis
Gardaí say they will issue a further update in two hours or less.