The charity says behaviours like withdrawing from friends and family or extreme changes in mood are signs someone could be struggling.
The latest figures from the CSO show 437 people died by suicide in Ireland in 2018.
Tom McEvoy of Pieta House, says listening support is there for anyone who's struggling with their mental health:
In the best way possible. Describe how you feel that you're very low perhaps that you are seeing no future, maybe, reaching out for that help can save a life can save your life. Maybe you know that 1800 247247 number your furniture is a lifeline, it's a crisis helpline people are on the other end of that line, who aren't able to help you, so we can really help somebody who is struggling, and in a dark place.