There's a shortage of 248 medicines in the Irish market.
New figures from the Medicines Shortage Index show the figure marks an increase of 48% on last year's number.
Tablets for anxiety and insomnia are recorded as the lowest category in the Irish market.
Aideen Kenny of Azure Pharmaceuticals says supply-chain issues and rising costs are contributing to the shortages.
"We're seeing supply chain issues for sure, but in addition and specifically the reason we'd like to draw attention to this in Ireland is that we're noticing commercial reasons as becoming more and more relevant for precipitating medicines in pharmaceutical medicines here."