Jeremy Loughman has been called up to the Ireland squad.
The Munster loosehead prop has been drafted into the camp for the clash with England on Saturday following the injury to Andrew Porter.
It's the first time that the 26 year old has been called up to the Ireland squad.
Iain Henderson meanwhile has returned to the camp after missing the win over Italy due to a positive Covid 19 test, while Jordan Larmour has been ruled out for the remaining two games of the championship due to a hip injury picked up on Leinster duty away to Bennetton.
Jack Carty, Dave Heffernan (Connacht), Craig Casey, Gavin Coombes (Munster) and Robert Baloucoune, James Hume and Nick Timoney (Ulster) all return to the Ireland squad having featured for their respective provinces.
Ireland Squad Round 4 2022 Guinness Six Nations Championships
Backs (16)
Bundee Aki (Connacht/Galwegians) 35 caps
Robert Baloucoune (Ulster/Enniskillen) 2 caps
Joey Carbery (Munster/Clontarf) 30 caps
Jack Carty (Buccaneers/Connacht) 11 caps
Craig Casey (Munster/Shannon) 5 caps
Andrew Conway (Munster/Garryowen) 29 caps
Jamison Gibson Park (Leinster) 15 caps
Mack Hansen (Connacht) 3 caps
Robbie Henshaw (Leinster/Buccaneers) 55 caps
James Hume (Ulster/Banbridge) 3 caps
Hugo Keenan (Leinster/UCD) 18 caps
James Lowe (Leinster) 10 caps
Michael Lowry (Ulster/Banbridge) 1 cap
Conor Murray (Munster/Garryowen) 94 caps
Garry Ringrose (Leinster/UCD) 40 caps
Johnny Sexton (Leinster/St Mary’s College) 103 caps CAPTAIN
Forwards (19)
Ryan Baird (Leinster/Dublin University) 8 caps
Finlay Bealham (Connacht/Buccaneers) 21 caps
Tadhg Beirne (Munster/Lansdowne) 28 caps
Jack Conan (Leinster/Old Belvedere) 25 caps
Gavin Coombes (Munster/Young Munster) 2 caps
Caelan Doris (Leinster/St Mary’s College) 15 caps
Tadhg Furlong (Leinster/Clontarf) 55 caps
Cian Healy (Leinster/Clontarf) 114 caps
Dave Heffernan (Connacht/Buccaneers) 6 caps
Iain Henderson (Ulster/Academy) 66 caps
Rob Herring (Ulster/Ballynahinch) 24 caps
Dave Kilcoyne (Munster/UL Bohemians) 46 caps
Jeremy Loughman (Munster/Garryowen) uncapped
Peter O’Mahony (Munster/Cork Constitution) 82 caps
James Ryan (Leinster/UCD) 42 caps
Dan Sheehan (Leinster/Lansdowne) 5 caps
Nick Timoney (Ulster/Banbridge) 2 caps
Kieran Treadwell (Ulster/Ballymena) 4 caps
Josh van der Flier (Leinster/UCD) 38 caps