Champions Manchester City will begin the defence of their Premier League title with a trip to West Ham
Newly-promoted Fulham host Jurgen Klopp's Liverpool, while Nottingham Forest's first top flight game in 23 years will be away at Newcastle.
Erik ten Hag will hope to get his reign as Manchester United boss off to a winning start at Old Trafford when they take on Brighton.
Next season will feature a winter break between the 12th of November and the 26th of December due to the World Cup in Qatar.
Matchday 1 - August 6
- Crystal Palace v Arsenal - August 5 - 8pm
- Fulham v Liverpool - August 6 - 12:30pm
- Bournemouth v Aston Villa - August 6 - 3pm
- Leeds United v Wolverhampton - August 6 - 3pm
- Leicester City v Brentford - August 6 - 3pm
- Newcastle United v Nottingham Forest - August 6 - 3pm
- Tottenham Hotspur v Southampton - August 6 - 3pm
- Everton v Chelsea - August 6 - 5:30pm
- Manchester United v Brighton - August 7 - 2pm
- West Ham United v Manchester City - August 7 - 4:30pm